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Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice
BACKGROUND: Highly pathogenic avian influenza virus (HPAIV) causes a highly contagious often fatal disease in poultry, resulting in significant economic losses in the poultry industry. HPAIV H5N1 also poses a major public health threat as it can be transmitted directly from infected poultry to human...
Autores principales: | Cornelissen, Lisette A. H. M., de Leeuw, Olav S., Tacken, Mirriam G., Klos, Heleen C., de Vries, Robert P., de Boer-Luijtze, Els A., van Zoelen-Bos, Diana J., Rigter, Alan, Rottier, Peter J. M., Moormann, Rob J. M., de Haan, Cornelis A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429475/ https://www.ncbi.nlm.nih.gov/pubmed/22952980 http://dx.doi.org/10.1371/journal.pone.0044447 |
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