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PNA bearing 5-azidomethyluracil: A novel approach for solid and solution phase modification
Fmoc- and Boc-protected modified monomers bearing 5-azidomethyluracil nucleobase were synthesized. Four different solid-phase synthetic strategies were tested in order to evaluate the application of this series of monomers for the solid-phase synthesis of modified PNA. The azide was used as masked a...
Autores principales: | Manicardi, Alex, Accetta, Alessandro, Tedeschi, Tullia, Sforza, Stefano, Marchelli, Rosangela, Corradini, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429531/ https://www.ncbi.nlm.nih.gov/pubmed/22772040 http://dx.doi.org/10.4161/adna.20158 |
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