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Introduction of multiphosphonate ligand to peptide nucleic acid for metal ion conjugation
Peptide nucleic acid (PNA) is one of the most widely used synthetic DNA analogs. Conjugation of functional molecules to PNA is very effective to further widen its potential applications. For this purpose, here we report the synthesis of several ligand monomers and introduced them to PNA. These ligan...
Autores principales: | Aiba, Yuichiro, Honda, Yuta, Han, Yue, Komiyama, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429533/ https://www.ncbi.nlm.nih.gov/pubmed/22772037 http://dx.doi.org/10.4161/adna.20727 |
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