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Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

Tobacco smoke-induced accelerated cell senescence has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cell senescence is accompanied by the accumulation of damaged cellular components suggesting that in COPD, inhibition of autophagy may contribute to cell senesce...

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Detalles Bibliográficos
Autores principales:	Fujii, Satoko, Hara, Hiromichi, Araya, Jun, Takasaka, Naoki, Kojima, Jun, Ito, Saburo, Minagawa, Shunsuke, Yumino, Yoko, Ishikawa, Takeo, Numata, Takanori, Kawaishi, Makoto, Hirano, Jun, Odaka, Makoto, Morikawa, Toshiaki, Nishimura, Stephen, Nakayama, Katsutoshi, Kuwano, Kazuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429567/ https://www.ncbi.nlm.nih.gov/pubmed/22934255 http://dx.doi.org/10.4161/onci.20297

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