Cytomegalovirus infection in brain tumors: A potential new target for therapy?

Emerging evidence demonstrate a high prevalence of cytomegalovirus (CMV) proteins and nucleic acids in different tumors. CMV is confined to tumor cells and non-cancer cells in close proximity to tumors are consistently virus negative. CMV confers both oncogenic and oncomodulatory mechanisms, and may...

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Autores principales: Söderberg-Nauclér, Cecilia, Johnsen, John Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429578/
https://www.ncbi.nlm.nih.gov/pubmed/22934266
http://dx.doi.org/10.4161/onci.19441
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author Söderberg-Nauclér, Cecilia
Johnsen, John Inge
author_facet Söderberg-Nauclér, Cecilia
Johnsen, John Inge
author_sort Söderberg-Nauclér, Cecilia
collection PubMed
description Emerging evidence demonstrate a high prevalence of cytomegalovirus (CMV) proteins and nucleic acids in different tumors. CMV is confined to tumor cells and non-cancer cells in close proximity to tumors are consistently virus negative. CMV confers both oncogenic and oncomodulatory mechanisms, and may therefore provide a novel target in cancer treatment.
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spelling pubmed-34295782012-08-29 Cytomegalovirus infection in brain tumors: A potential new target for therapy? Söderberg-Nauclér, Cecilia Johnsen, John Inge Oncoimmunology Author's View Emerging evidence demonstrate a high prevalence of cytomegalovirus (CMV) proteins and nucleic acids in different tumors. CMV is confined to tumor cells and non-cancer cells in close proximity to tumors are consistently virus negative. CMV confers both oncogenic and oncomodulatory mechanisms, and may therefore provide a novel target in cancer treatment. Landes Bioscience 2012-08-01 /pmc/articles/PMC3429578/ /pubmed/22934266 http://dx.doi.org/10.4161/onci.19441 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Söderberg-Nauclér, Cecilia
Johnsen, John Inge
Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title_full Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title_fullStr Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title_full_unstemmed Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title_short Cytomegalovirus infection in brain tumors: A potential new target for therapy?
title_sort cytomegalovirus infection in brain tumors: a potential new target for therapy?
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429578/
https://www.ncbi.nlm.nih.gov/pubmed/22934266
http://dx.doi.org/10.4161/onci.19441
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