Insight into the dynamics, localization and magnitude of antigen-specific immune responses by [(18)F]FLT PET imaging

In order for cellular therapeutics to succeed, comprehensive monitoring of the transplanted cells in vivo is required i.e., their localization, functionality and numbers in a longitudinal manner. Recently, dendritic cell based vaccines have been monitored by their effect on lymphocyte activation usi...

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Detalles Bibliográficos
Autores principales: Aarntzen, Erik H.J.G., Srinivas, Mangala, Punt, Cornelius J.A., Figdor, Carl G., Oyen, Wim J.G., de Vries, I. Jolanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429580/
https://www.ncbi.nlm.nih.gov/pubmed/22934268
http://dx.doi.org/10.4161/onci.19533
Descripción
Sumario:In order for cellular therapeutics to succeed, comprehensive monitoring of the transplanted cells in vivo is required i.e., their localization, functionality and numbers in a longitudinal manner. Recently, dendritic cell based vaccines have been monitored by their effect on lymphocyte activation using [(18)F]FLT PET in cancer patients.

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