DKK1 as a novel target for myeloma immunotherapy

Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 c...

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Detalles Bibliográficos
Autores principales: Qian, Jianfei, Yi, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429585/
https://www.ncbi.nlm.nih.gov/pubmed/22934273
http://dx.doi.org/10.4161/onci.19655
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author Qian, Jianfei
Yi, Qing
author_facet Qian, Jianfei
Yi, Qing
author_sort Qian, Jianfei
collection PubMed
description Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 could be developed as a novel vaccine for myeloma immunotherapy.
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spelling pubmed-34295852012-08-29 DKK1 as a novel target for myeloma immunotherapy Qian, Jianfei Yi, Qing Oncoimmunology Author's View Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 could be developed as a novel vaccine for myeloma immunotherapy. Landes Bioscience 2012-08-01 /pmc/articles/PMC3429585/ /pubmed/22934273 http://dx.doi.org/10.4161/onci.19655 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Qian, Jianfei
Yi, Qing
DKK1 as a novel target for myeloma immunotherapy
title DKK1 as a novel target for myeloma immunotherapy
title_full DKK1 as a novel target for myeloma immunotherapy
title_fullStr DKK1 as a novel target for myeloma immunotherapy
title_full_unstemmed DKK1 as a novel target for myeloma immunotherapy
title_short DKK1 as a novel target for myeloma immunotherapy
title_sort dkk1 as a novel target for myeloma immunotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429585/
https://www.ncbi.nlm.nih.gov/pubmed/22934273
http://dx.doi.org/10.4161/onci.19655
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AT yiqing dkk1asanoveltargetformyelomaimmunotherapy

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