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DKK1 as a novel target for myeloma immunotherapy

Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 c...

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Detalles Bibliográficos
Autores principales: Qian, Jianfei, Yi, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429585/
https://www.ncbi.nlm.nih.gov/pubmed/22934273
http://dx.doi.org/10.4161/onci.19655