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New strategies for melanoma immunotherapy: How to overcome immunosuppression in the tumor microenvironment
Using ret transgenic mouse model of spontaneous melanoma, we showed an accumulation of melanoma antigen-specific memory T cells. However, their antitumor effects could be blocked by myeloid-derived suppressor cells, tolerogenic dendritic cells and regulatory T cells. We suggest that effective melano...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429588/ https://www.ncbi.nlm.nih.gov/pubmed/22934276 http://dx.doi.org/10.4161/onci.19713 |