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Effect of CpG ODN on monocytic myeloid derived suppressor cells

CpG oligonucleotides stimulate via TLR9 and enhance anti-tumor immunity, an effect attributed to the activation of NK and CD8(+) T cells. Our recent work demonstrates that CpG ODN also induce monocytic myeloid-derived suppressor cells to mature into M1 macrophages, further aiding tumor elimination....

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Detalles Bibliográficos
Autores principales:	Shirota, Hidekazu, Klinman, Dennis M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429593/ https://www.ncbi.nlm.nih.gov/pubmed/22934281 http://dx.doi.org/10.4161/onci.19731

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