IL-17A is a central regulator of lung tumor growth

In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumo...

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Detalles Bibliográficos
Autores principales: Reppert, Sarah, Koch, Sonja, Finotto, Susetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429594/
https://www.ncbi.nlm.nih.gov/pubmed/22934282
http://dx.doi.org/10.4161/onci.19735
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author Reppert, Sarah
Koch, Sonja
Finotto, Susetta
author_facet Reppert, Sarah
Koch, Sonja
Finotto, Susetta
author_sort Reppert, Sarah
collection PubMed
description In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumor growth.
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spelling pubmed-34295942012-08-29 IL-17A is a central regulator of lung tumor growth Reppert, Sarah Koch, Sonja Finotto, Susetta Oncoimmunology Author's View In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumor growth. Landes Bioscience 2012-08-01 /pmc/articles/PMC3429594/ /pubmed/22934282 http://dx.doi.org/10.4161/onci.19735 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Reppert, Sarah
Koch, Sonja
Finotto, Susetta
IL-17A is a central regulator of lung tumor growth
title IL-17A is a central regulator of lung tumor growth
title_full IL-17A is a central regulator of lung tumor growth
title_fullStr IL-17A is a central regulator of lung tumor growth
title_full_unstemmed IL-17A is a central regulator of lung tumor growth
title_short IL-17A is a central regulator of lung tumor growth
title_sort il-17a is a central regulator of lung tumor growth
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429594/
https://www.ncbi.nlm.nih.gov/pubmed/22934282
http://dx.doi.org/10.4161/onci.19735
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