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IL-17A is a central regulator of lung tumor growth
In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumo...
Autores principales: | Reppert, Sarah, Koch, Sonja, Finotto, Susetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429594/ https://www.ncbi.nlm.nih.gov/pubmed/22934282 http://dx.doi.org/10.4161/onci.19735 |
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