TG4010: A therapeutic vaccine against MUC1 expressing tumors

TG4010 is a therapeutic cancer vaccine based on a viral vector, a modified vaccinia of Ankara (MVA), expressing MUC1 as well as interleukine 2. Today the clinical development is focused on advanced non-small cell lung cancer in combination with first line chemotherapy. Potential biomarkers predictiv...

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Detalles Bibliográficos
Autores principales: Limacher, Jean-Marc, Quoix, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429597/
https://www.ncbi.nlm.nih.gov/pubmed/22934285
http://dx.doi.org/10.4161/onci.19863
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author Limacher, Jean-Marc
Quoix, Elisabeth
author_facet Limacher, Jean-Marc
Quoix, Elisabeth
author_sort Limacher, Jean-Marc
collection PubMed
description TG4010 is a therapeutic cancer vaccine based on a viral vector, a modified vaccinia of Ankara (MVA), expressing MUC1 as well as interleukine 2. Today the clinical development is focused on advanced non-small cell lung cancer in combination with first line chemotherapy. Potential biomarkers predictive of activity have been identified.
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spelling pubmed-34295972012-08-29 TG4010: A therapeutic vaccine against MUC1 expressing tumors Limacher, Jean-Marc Quoix, Elisabeth Oncoimmunology Author's View TG4010 is a therapeutic cancer vaccine based on a viral vector, a modified vaccinia of Ankara (MVA), expressing MUC1 as well as interleukine 2. Today the clinical development is focused on advanced non-small cell lung cancer in combination with first line chemotherapy. Potential biomarkers predictive of activity have been identified. Landes Bioscience 2012-08-01 /pmc/articles/PMC3429597/ /pubmed/22934285 http://dx.doi.org/10.4161/onci.19863 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Limacher, Jean-Marc
Quoix, Elisabeth
TG4010: A therapeutic vaccine against MUC1 expressing tumors
title TG4010: A therapeutic vaccine against MUC1 expressing tumors
title_full TG4010: A therapeutic vaccine against MUC1 expressing tumors
title_fullStr TG4010: A therapeutic vaccine against MUC1 expressing tumors
title_full_unstemmed TG4010: A therapeutic vaccine against MUC1 expressing tumors
title_short TG4010: A therapeutic vaccine against MUC1 expressing tumors
title_sort tg4010: a therapeutic vaccine against muc1 expressing tumors
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429597/
https://www.ncbi.nlm.nih.gov/pubmed/22934285
http://dx.doi.org/10.4161/onci.19863
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