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Optimized models for design of efficient miR30-based shRNAs

Small hairpin RNAs (shRNAs) became an important research tool in cell biology. Reliable design of these molecules is essential for the needs of large functional genomics projects. To optimize the design of efficient shRNAs, we performed comparative, thermodynamic, and correlation analyses of ~18,000...

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Detalles Bibliográficos
Autores principales:	Matveeva, Olga V., Nazipova, Nafisa N., Ogurtsov, Aleksey Y., Shabalina, Svetlana A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429853/ https://www.ncbi.nlm.nih.gov/pubmed/22952469 http://dx.doi.org/10.3389/fgene.2012.00163

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