Cargando…

Ex vivo stimulation of whole blood as a means to determine glucocorticoid sensitivity

PURPOSE: Glucocorticoids are commonly prescribed to treat a number of diseases including the majority of inflammatory diseases. Despite considerable interpersonal variability in response to glucocorticoids, an insensitivity rate of about 30%, and the risk of adverse side effects of glucocorticoid th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burnsides, Christopher, Corry, Jacqueline, Alexander, Jacob, Balint, Catherine, Cosmar, David, Phillips, Gary, Marketon, Jeanette I Webster
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430009/ https://www.ncbi.nlm.nih.gov/pubmed/22952414 http://dx.doi.org/10.2147/JIR.S33569

Ejemplares similares

Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation()
por: Webster Marketon, Jeanette I., et al.
Publicado: (2013)

The Glucocorticoid Receptor: A Revisited Target for Toxins
por: Marketon, Jeanette I. Webster, et al.
Publicado: (2010)

Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma
por: Lohse, Ines, et al.
Publicado: (2018)

Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs
por: Lerch, Jessica K., et al.
Publicado: (2017)

Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
por: Gugliandolo, Enrico, et al.
Publicado: (2021)

Ex vivo glucocorticoid receptor-mediated IL-10 response predicts the course of depression severity
por: von Zimmermann, Claudia, et al.
Publicado: (2021)

Melatonin as a potential therapy for sepsis: a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis
por: Galley, Helen F, et al.
Publicado: (2014)

Decreased whole blood TNFα production capacity after acute alcohol exposure and LPS stimulation ex vivo
por: Gavala, A, et al.
Publicado: (2010)

Whole-brain ex-vivo quantitative MRI of the cuprizone mouse model
por: Wood, Tobias C., et al.
Publicado: (2016)

Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo
por: Barington, Maria, et al.
Publicado: (2017)

A preliminary study assessing cytokine production following ex vivo stimulation of whole blood with diet in dogs with chronic enteropathy
por: Kathrani, Aarti, et al.
Publicado: (2019)

Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo
por: Westman, Johannes, et al.
Publicado: (2015)

Ex vivo Comprehensive Multiphase NMR of whole organisms: A complementary tool to in vivo NMR
por: Ghosh Biswas, Rajshree, et al.
Publicado: (2020)

Comparison of host immune responses to LPS in human using an immune profiling panel, in vivo endotoxemia versus ex vivo stimulation
por: Tawfik, Dina M., et al.
Publicado: (2020)

Sensitivity and resistance to glucocorticoids
por: Chrousos, George
Publicado: (2014)

The Effects of Ex Vivo Administration of Granulocyte-Macrophage Colony-Stimulating Factor and Endotoxin on Cytokine Release of Whole Blood Are Determined by Priming Conditions
por: Nierhaus, A., et al.
Publicado: (2017)

Deleterious effects of whole‐body vibration on the spine: A review of in vivo, ex vivo, and in vitro models
por: Patterson, Folly, et al.
Publicado: (2021)

An ex vivo RT-qPCR-based assay for human peripheral leukocyte responsiveness to glucocorticoids in surgically induced inflammation
por: Gråberg, Truls, et al.
Publicado: (2015)

Isolation and enrichment of mouse splenic T cells for ex vivo and in vivo T cell receptor stimulation assays
por: Grosjean, Clémence, et al.
Publicado: (2021)

Human colon function ex vivo: Dependence on oxygen and sensitivity to antibiotic
por: Schwerdtfeger, Luke A., et al.
Publicado: (2019)

Ex vivo evaluation of antibiotic sensitivity in samples from endodontic infections
por: Villanueva-Castellote, Álvaro, et al.
Publicado: (2022)

Ex vivo assessment of chemotherapy sensitivity of colorectal cancer peritoneal metastases
por: Cashin, Peter H, et al.
Publicado: (2023)

EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration
por: Durhuus, Jon Ambæk, et al.
Publicado: (2021)

Influence of embedding media on the accuracy of working length determination by means of apex locator: an ex vivo study
por: Wolf, Thomas Gerhard, et al.
Publicado: (2021)

X-ray dark-field radiography for in situ gout diagnosis by means of an ex vivo animal study
por: Scholz, Josef, et al.
Publicado: (2021)

Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia
por: Legebeke, Jelmer, et al.
Publicado: (2022)

Ex vivo instability of lipids in whole blood: preanalytical recommendations for clinical lipidomics studies
por: Wang, Qingqing, et al.
Publicado: (2023)

The effect of whole blood logistics on neutrophil non-specific activation and kinetics ex vivo
por: Li, Chao, et al.
Publicado: (2023)

Glucocorticoid sensitivity in Behçet's disease
por: Quax, R A M, et al.
Publicado: (2012)

In vitro and ex vivo systems at the forefront of infection modeling and drug discovery
por: Shi, Di, et al.
Publicado: (2019)

Protocol for in vivo and ex vivo assessments of glucose-stimulated insulin secretion in mouse islet β cells
por: Zhu, Yun-Xia, et al.
Publicado: (2021)

Humoral Responses and Ex Vivo IFN-γ Production after Canine Whole Blood Stimulation with Leishmania infantum Antigen or KMP11 Recombinant Protein
por: Martínez-Orellana, Pamela, et al.
Publicado: (2022)

Topical Delivery of Rapamycin by Means of Microenvironment-Sensitive Core-Multi-Shell Nanocarriers: Assessment of Anti-Inflammatory Activity in an ex vivo Skin/T Cell Co-Culture Model
por: Rancan, Fiorenza, et al.
Publicado: (2021)

Functional Ex Vivo Tissue-Based Chemotherapy Sensitivity Testing for Breast Cancer
por: Ladan, Marjolijn M., et al.
Publicado: (2022)

A Method for Whole Brain Ex Vivo Magnetic Resonance Imaging with Minimal Susceptibility Artifacts
por: Shatil, Anwar S., et al.
Publicado: (2016)

Spatial Characterization of Bioenergetics and Metabolism of Primordial to Preovulatory Follicles in Whole Ex Vivo Murine Ovary
por: Cinco, Rachel, et al.
Publicado: (2016)

Granulocyte-Colony Stimulating Factor Related Pathways Tested on an Endometrial Ex-Vivo Model
por: Rahmati, Mona, et al.
Publicado: (2014)

Protamine-stabilized RNA as an ex vivo stimulant of primary human dendritic cell subsets
por: Sköld, Annette E., et al.
Publicado: (2015)

Prototype chemical synapse chip for spatially patterned neurotransmitter stimulation of the retina ex vivo
por: Rountree, Corey M., et al.
Publicado: (2017)

Functional studies of intimin in vivo and ex vivo: implications for host specificity and tissue tropism
por: Mundy, Rosanna, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6jp3rlen4ttmbl75crm7qf6mrl