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Phage Display-based Strategies for Cloning and Optimization of Monoclonal Antibodies Directed against Human Pathogens

In the last two decades, several phage display-selected monoclonal antibodies (mAbs) have been described in the literature and a few of them have managed to reach the clinics. Among these, the anti-respiratory syncytial virus (RSV) Palivizumab, a phage-display optimized mAb, is the only marketed mAb...

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Detalles Bibliográficos
Autores principales: Clementi, Nicola, Mancini, Nicasio, Solforosi, Laura, Castelli, Matteo, Clementi, Massimo, Burioni, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430233/
https://www.ncbi.nlm.nih.gov/pubmed/22942702
http://dx.doi.org/10.3390/ijms13078273