Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice

The mechanisms underlying the pathogenesis of idiopathic pulmonary fibrosis (IPF) involve multiple pathways, such as inflammation, epithelial mesenchymal transition, coagulation, oxidative stress, and developmental processes. The small GTPase, RhoA, and its target protein, Rho-kinase (ROCK), may int...

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Detalles Bibliográficos
Autores principales: Jiang, Chunguo, Huang, Hui, Liu, Jia, Wang, Yanxun, Lu, Zhiwei, Xu, Zuojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430234/
https://www.ncbi.nlm.nih.gov/pubmed/22942703
http://dx.doi.org/10.3390/ijms13078293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430234/
https://www.ncbi.nlm.nih.gov/pubmed/22942703
http://dx.doi.org/10.3390/ijms13078293

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