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Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
The mechanisms underlying the pathogenesis of idiopathic pulmonary fibrosis (IPF) involve multiple pathways, such as inflammation, epithelial mesenchymal transition, coagulation, oxidative stress, and developmental processes. The small GTPase, RhoA, and its target protein, Rho-kinase (ROCK), may int...
Autores principales: | Jiang, Chunguo, Huang, Hui, Liu, Jia, Wang, Yanxun, Lu, Zhiwei, Xu, Zuojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430234/ https://www.ncbi.nlm.nih.gov/pubmed/22942703 http://dx.doi.org/10.3390/ijms13078293 |
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