Chemopreventive Efficacy of Atorvastatin against Nitrosamine-Induced Rat Bladder Cancer: Antioxidant, Anti-Proliferative and Anti-Inflammatory Properties

To investigate the anti-carcinogenic effects of Atorvastatin (Atorva) on a rat bladder carcinogenesis model with N-butyl-N-(4-hydroxibutil)nitrosamine (BBN), four male Wistar rat groups were studied: (1) Control: vehicle; (2) Atorva: 3 mg/kg bw/day; (3) Carcinogen: BBN (0.05%); (4) Preventive Atorva...

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Detalles Bibliográficos
Autores principales: Parada, Belmiro, Reis, Flávio, Pinto, Ângela, Sereno, José, Xavier-Cunha, Maria, Neto, Paula, Rocha-Pereira, Petronila, Mota, Alfredo, Figueiredo, Arnaldo, Teixeira, Frederico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430246/
https://www.ncbi.nlm.nih.gov/pubmed/22942715
http://dx.doi.org/10.3390/ijms13078482

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