Leukocyte Mitochondrial DNA Alteration in Systemic Lupus Erythematosus and Its Relevance to the Susceptibility to Lupus Nephritis

The role of mitochondrial DNA (mtDNA) alterations in the pathophysiology of systemic lupus erythematosus (SLE) remains unclear. We investigated sequence variations in the D310 region and copy number change of mtDNA in 85 SLE patients and 45 normal subjects. Leukocyte DNA and RNA were extracted from...

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Detalles Bibliográficos
Autores principales: Lee, Hui-Ting, Lin, Chen-Sung, Chen, Wei-Sheng, Liao, Hsien-Tzung, Tsai, Chang-Youh, Wei, Yau-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430270/
https://www.ncbi.nlm.nih.gov/pubmed/22942739
http://dx.doi.org/10.3390/ijms13078853

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