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The Apoptotic Volume Decrease Is an Upstream Event of MAP Kinase Activation during Staurosporine-Induced Apoptosis in HeLa Cells

Persistent cell shrinkage, called apoptotic volume decrease (AVD), is a pivotal event of apoptosis. Activation of the volume-sensitive outwardly rectifying Cl(−) channel (VSOR) is involved in the AVD induction. On the other hand, activation of the MAP kinase (MAPK) cascade is also known to play a cr...

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Detalles Bibliográficos
Autores principales:	Hasegawa, Yuichi, Shimizu, Takahiro, Takahashi, Nobuyuki, Okada, Yasunobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430301/ https://www.ncbi.nlm.nih.gov/pubmed/22942770 http://dx.doi.org/10.3390/ijms13079363

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