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BNIP3 is Essential for Mediating 6-thioguanine-and 5-fluorouracil-induced Autophagy Following DNA Mismatch Repair Processing

DNA mismatch repair (MMR) processes the chemically-induced mispairs following treatment with clinically important nucleoside analogs such as 6-thioguanine (6-TG) and 5-fluorouracil (5-FU). MMR processing of these drugs has been implicated in activation of a prolonged G(2)/M cell cycle arrest for rep...

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Detalles Bibliográficos
Autores principales: Zeng, Xuehuo, Kinsella, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430372/
https://www.ncbi.nlm.nih.gov/pubmed/20368736
http://dx.doi.org/10.1038/cr.2010.40