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Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice

Sphingosine 1-Phosphate Receptor 1 (S1P(1)) plays a critical role in lymphocyte recirculation and is a clinical target for treatment of multiple sclerosis. By generating a short-duration S1P(1) agonist and mice where fluorescently tagged S1P(1) replaces wild-type receptor, we elucidate physiological...

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Detalles Bibliográficos
Autores principales:	Cahalan, Stuart M., Gonzalez-Cabrera, Pedro J., Sarkisyan, Gor, Nguyen, Nhan, Schaeffer, Marie-Therese, Huang, Liming, Yeager, Adam, Clemons, Bryan, Scott, Fiona, Rosen, Hugh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430385/ https://www.ncbi.nlm.nih.gov/pubmed/21445057 http://dx.doi.org/10.1038/nchembio.547

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