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Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study

OBJECTIVE: We conducted a double-blind, placebo-controlled study to determine the efficacy of an herbal sexual supplement (vigRX) on premature ejaculation (PE). METHOD: A randomized double blind study was conducted on a fixed dose of herbal vigRX at Roozbeh Psychiatry Hospital, Tehran University of...

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Autores principales: Raisi, Firoozeh, Farnia, Vahid, Ghanbarian, Nafiseh, Ghafuri, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430409/
https://www.ncbi.nlm.nih.gov/pubmed/22952482
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author Raisi, Firoozeh
Farnia, Vahid
Ghanbarian, Nafiseh
Ghafuri, Z.
author_facet Raisi, Firoozeh
Farnia, Vahid
Ghanbarian, Nafiseh
Ghafuri, Z.
author_sort Raisi, Firoozeh
collection PubMed
description OBJECTIVE: We conducted a double-blind, placebo-controlled study to determine the efficacy of an herbal sexual supplement (vigRX) on premature ejaculation (PE). METHOD: A randomized double blind study was conducted on a fixed dose of herbal vigRX at Roozbeh Psychiatry Hospital, Tehran University of Medical Sciences. The sample consisted of 85 married patients diagnosed with primary PE according to Diagnostic and Statistical Manual of Mental Disorders. Each patient underwent diagnostic evaluation by one trained psychiatrist, using Structured Clinical Interview for DSM-IV-TR. Each patient was evaluated by researchers to exclude the organic sexual dysfunctions. The patients were randomly assigned in to two groups: group 1 consisting of 42 patients receiving placebo, and group 2 consisting of 43 patients receiving 540 mg herbal vigRX for a 4-week treatment course. The effects of the drug on the ejaculatory function in each group were assessed by the intravaginal ejaculation latency time (IELT), and the Chinese Index of Premature Ejaculation (CIPE) before and at the end of the treatment course. Statistical analysis was performed using SPSS software (15th version). RESULTS: The mean IELT increased 22.4 and 32.0 seconds in the placebo and the vigRX group respectively after the treatment course. The mean IELT differences between the two groups was not significant. The mean CIPE score increased 2.40 and 4.37 in the placebo and the vigRX group respectively. The mean CIPE score differences between the two groups was not significant.No side effect was reported by the subjects in neither groups during the treatment course. CONCLUSION: Although the improvement in IELT and CIPE scores in the herbal vigRX group was more than the placebo group, this difference was not statistically significant. The increasing of IELT and CIPE score in the placebo group may be due to the placebo effects. Further studies with higher vigRX doses, greater sample size and longer treatment courses are warranted.
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spelling pubmed-34304092012-09-05 Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study Raisi, Firoozeh Farnia, Vahid Ghanbarian, Nafiseh Ghafuri, Z. Iran J Psychiatry Original Article OBJECTIVE: We conducted a double-blind, placebo-controlled study to determine the efficacy of an herbal sexual supplement (vigRX) on premature ejaculation (PE). METHOD: A randomized double blind study was conducted on a fixed dose of herbal vigRX at Roozbeh Psychiatry Hospital, Tehran University of Medical Sciences. The sample consisted of 85 married patients diagnosed with primary PE according to Diagnostic and Statistical Manual of Mental Disorders. Each patient underwent diagnostic evaluation by one trained psychiatrist, using Structured Clinical Interview for DSM-IV-TR. Each patient was evaluated by researchers to exclude the organic sexual dysfunctions. The patients were randomly assigned in to two groups: group 1 consisting of 42 patients receiving placebo, and group 2 consisting of 43 patients receiving 540 mg herbal vigRX for a 4-week treatment course. The effects of the drug on the ejaculatory function in each group were assessed by the intravaginal ejaculation latency time (IELT), and the Chinese Index of Premature Ejaculation (CIPE) before and at the end of the treatment course. Statistical analysis was performed using SPSS software (15th version). RESULTS: The mean IELT increased 22.4 and 32.0 seconds in the placebo and the vigRX group respectively after the treatment course. The mean IELT differences between the two groups was not significant. The mean CIPE score increased 2.40 and 4.37 in the placebo and the vigRX group respectively. The mean CIPE score differences between the two groups was not significant.No side effect was reported by the subjects in neither groups during the treatment course. CONCLUSION: Although the improvement in IELT and CIPE scores in the herbal vigRX group was more than the placebo group, this difference was not statistically significant. The increasing of IELT and CIPE score in the placebo group may be due to the placebo effects. Further studies with higher vigRX doses, greater sample size and longer treatment courses are warranted. Tehran University of Medical Sciences 2010 /pmc/articles/PMC3430409/ /pubmed/22952482 Text en © 2010 Psychiatry and Psychology Research Center, Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Raisi, Firoozeh
Farnia, Vahid
Ghanbarian, Nafiseh
Ghafuri, Z.
Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title_full Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title_fullStr Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title_full_unstemmed Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title_short Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study
title_sort effects of herbal vigrx on premature ejaculation: a randomized, double-blind study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430409/
https://www.ncbi.nlm.nih.gov/pubmed/22952482
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