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Regulation of PUMA induced by mechanical stress in rat cardiomyocytes

BACKGROUND: PUMA (p53-up-regulated modulator of apoptosis), an apoptosis regulated gene, increased during endoplasmic reticulum stress. However, the expression of PUMA in cardiomyocytes under mechanical stress is little known. We aimed to investigate the regulation mechanism of PUMA expression and a...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Pin, Wu, Gong-Jhe, Wang, Bao-Wei, Shyu, Kou-Gi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430577/
https://www.ncbi.nlm.nih.gov/pubmed/22862895
http://dx.doi.org/10.1186/1423-0127-19-72