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Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis

BACKGROUND: Warfarin is a highly effective anticoagulant however its effectiveness relies on maintaining INR in therapeutic range. Finding the correct dose is difficult due to large inter-individual variability. Two genes, CYP2C9 and VKORC1, have been associated with this variability, leading to gen...

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Detalles Bibliográficos
Autores principales:	Jorgensen, Andrea L., FitzGerald, Richard J., Oyee, James, Pirmohamed, Munir, Williamson, Paula R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430615/ https://www.ncbi.nlm.nih.gov/pubmed/22952875 http://dx.doi.org/10.1371/journal.pone.0044064

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