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Cortactin as a Target for FAK in the Regulation of Focal Adhesion Dynamics
BACKGROUND: Efficient cell movement requires the dynamic regulation of focal adhesion (FA) formation and turnover. FAs are integrin-associated sites of cell attachment and establish linkages to the cellular actin cytoskeleton. Cells without focal adhesion kinase (FAK), an integrin-activated tyrosine...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430618/ https://www.ncbi.nlm.nih.gov/pubmed/22952866 http://dx.doi.org/10.1371/journal.pone.0044041 |