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Cortactin as a Target for FAK in the Regulation of Focal Adhesion Dynamics

BACKGROUND: Efficient cell movement requires the dynamic regulation of focal adhesion (FA) formation and turnover. FAs are integrin-associated sites of cell attachment and establish linkages to the cellular actin cytoskeleton. Cells without focal adhesion kinase (FAK), an integrin-activated tyrosine...

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Detalles Bibliográficos
Autores principales:	Tomar, Alok, Lawson, Christine, Ghassemian, Majid, Schlaepfer, David D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430618/ https://www.ncbi.nlm.nih.gov/pubmed/22952866 http://dx.doi.org/10.1371/journal.pone.0044041

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