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Cigarette Smoking Decreases Global MicroRNA Expression in Human Alveolar Macrophages

Human alveolar macrophages are critical components of the innate immune system. Cigarette smoking-induced changes in alveolar macrophage gene expression are linked to reduced resistance to pulmonary infections and to the development of emphysema/COPD. We hypothesized that microRNAs (miRNAs) could co...

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Detalles Bibliográficos
Autores principales: Graff, Joel W., Powers, Linda S., Dickson, Anne M., Kim, Jongkwang, Reisetter, Anna C., Hassan, Ihab H., Kremens, Karol, Gross, Thomas J., Wilson, Mary E., Monick, Martha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430644/
https://www.ncbi.nlm.nih.gov/pubmed/22952876
http://dx.doi.org/10.1371/journal.pone.0044066