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N-Terminal Region of Gelsolin Induces Apoptosis of Activated Hepatic Stellate Cells by a Caspase-Dependent Mechanism

Activated hepatic stellate cells (HSCs) are the major source for alteration of extracellular matrix in fibrosis and cirrhosis. Conditioned medium (CM) collected from immortalized human hepatocytes (IHH) have earlier been shown to be responsible for apoptosis of HSCs. In this study, we have shown tha...

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Detalles Bibliográficos
Autores principales: Mazumdar, Budhaditya, Meyer, Keith, Ray, Ranjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430645/
https://www.ncbi.nlm.nih.gov/pubmed/22952982
http://dx.doi.org/10.1371/journal.pone.0044461