A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST)

BACKGROUND: In previous work, we designed a modified aptamer-free SELEX-seq protocol (afSELEX-seq) for the discovery of transcription factor binding sites. Here, we present original software, TFAST, designed to analyze afSELEX-seq data, validated against our previously generated afSELEX-seq dataset...

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Detalles Bibliográficos
Autores principales: Reiss, Daniel J., Howard, Frederick M., Mobley, Harry L. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430675/
https://www.ncbi.nlm.nih.gov/pubmed/22956994
http://dx.doi.org/10.1371/journal.pone.0042761

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