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Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study

PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (dive...

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Autores principales: Niikura, Ryota, Nagata, Naoyoshi, Akiyama, Junichi, Shimbo, Takuro, Uemura, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430839/
https://www.ncbi.nlm.nih.gov/pubmed/22354135
http://dx.doi.org/10.1007/s00384-012-1422-x
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author Niikura, Ryota
Nagata, Naoyoshi
Akiyama, Junichi
Shimbo, Takuro
Uemura, Naomi
author_facet Niikura, Ryota
Nagata, Naoyoshi
Akiyama, Junichi
Shimbo, Takuro
Uemura, Naomi
author_sort Niikura, Ryota
collection PubMed
description PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (diverticular bleeding)–control (diverticulosis) study. We prospectively collected information of habits, comorbidities, history of medications and symptoms by a questionnaire, and diagnosed diverticular bleeding and diverticulosis by colonoscopy. Logistic regression models were used to estimate odds ratio (OR) and 95% confidence interval (CI). RESULTS: A total of 254 patients (diverticular bleeding, 45; diverculosis, 209) were selected for analysis. Cluster (≥10 diverticula) type (OR, 4.0; 95% CI, 1.8–8.9), hypertension (OR, 2.2; 95% CI, 1.0–4.6), ischemic heart disease (OR, 2.4; 95% CI, 1.1–5.4), and chronic renal failure (OR, 6.4; 95% CI, 1.3–32) were independent risk factors for diverticular bleeding. CONCLUSIONS: Large number of diverticula, hypertension, and concomitant arteriosclerotic diseases including ischemic heart disease and chronic renal failure are risk factors for diverticular bleeding. This study identifies new information on the risk factors for diverticular bleeding.
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spelling pubmed-34308392012-09-06 Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study Niikura, Ryota Nagata, Naoyoshi Akiyama, Junichi Shimbo, Takuro Uemura, Naomi Int J Colorectal Dis Original Article PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (diverticular bleeding)–control (diverticulosis) study. We prospectively collected information of habits, comorbidities, history of medications and symptoms by a questionnaire, and diagnosed diverticular bleeding and diverticulosis by colonoscopy. Logistic regression models were used to estimate odds ratio (OR) and 95% confidence interval (CI). RESULTS: A total of 254 patients (diverticular bleeding, 45; diverculosis, 209) were selected for analysis. Cluster (≥10 diverticula) type (OR, 4.0; 95% CI, 1.8–8.9), hypertension (OR, 2.2; 95% CI, 1.0–4.6), ischemic heart disease (OR, 2.4; 95% CI, 1.1–5.4), and chronic renal failure (OR, 6.4; 95% CI, 1.3–32) were independent risk factors for diverticular bleeding. CONCLUSIONS: Large number of diverticula, hypertension, and concomitant arteriosclerotic diseases including ischemic heart disease and chronic renal failure are risk factors for diverticular bleeding. This study identifies new information on the risk factors for diverticular bleeding. Springer-Verlag 2012-02-22 2012 /pmc/articles/PMC3430839/ /pubmed/22354135 http://dx.doi.org/10.1007/s00384-012-1422-x Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Niikura, Ryota
Nagata, Naoyoshi
Akiyama, Junichi
Shimbo, Takuro
Uemura, Naomi
Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title_full Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title_fullStr Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title_full_unstemmed Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title_short Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
title_sort hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430839/
https://www.ncbi.nlm.nih.gov/pubmed/22354135
http://dx.doi.org/10.1007/s00384-012-1422-x
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