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Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study
PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (dive...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430839/ https://www.ncbi.nlm.nih.gov/pubmed/22354135 http://dx.doi.org/10.1007/s00384-012-1422-x |
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author | Niikura, Ryota Nagata, Naoyoshi Akiyama, Junichi Shimbo, Takuro Uemura, Naomi |
author_facet | Niikura, Ryota Nagata, Naoyoshi Akiyama, Junichi Shimbo, Takuro Uemura, Naomi |
author_sort | Niikura, Ryota |
collection | PubMed |
description | PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (diverticular bleeding)–control (diverticulosis) study. We prospectively collected information of habits, comorbidities, history of medications and symptoms by a questionnaire, and diagnosed diverticular bleeding and diverticulosis by colonoscopy. Logistic regression models were used to estimate odds ratio (OR) and 95% confidence interval (CI). RESULTS: A total of 254 patients (diverticular bleeding, 45; diverculosis, 209) were selected for analysis. Cluster (≥10 diverticula) type (OR, 4.0; 95% CI, 1.8–8.9), hypertension (OR, 2.2; 95% CI, 1.0–4.6), ischemic heart disease (OR, 2.4; 95% CI, 1.1–5.4), and chronic renal failure (OR, 6.4; 95% CI, 1.3–32) were independent risk factors for diverticular bleeding. CONCLUSIONS: Large number of diverticula, hypertension, and concomitant arteriosclerotic diseases including ischemic heart disease and chronic renal failure are risk factors for diverticular bleeding. This study identifies new information on the risk factors for diverticular bleeding. |
format | Online Article Text |
id | pubmed-3430839 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-34308392012-09-06 Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study Niikura, Ryota Nagata, Naoyoshi Akiyama, Junichi Shimbo, Takuro Uemura, Naomi Int J Colorectal Dis Original Article PURPOSE: Colonic diverticular bleeding is a major cause of lower gastrointestinal bleeding. However, a limited number of studies have been reported on the risk factors for diverticular bleeding. Our aim was to identify risk factors for diverticular bleeding. METHODS: Our study design is a case (diverticular bleeding)–control (diverticulosis) study. We prospectively collected information of habits, comorbidities, history of medications and symptoms by a questionnaire, and diagnosed diverticular bleeding and diverticulosis by colonoscopy. Logistic regression models were used to estimate odds ratio (OR) and 95% confidence interval (CI). RESULTS: A total of 254 patients (diverticular bleeding, 45; diverculosis, 209) were selected for analysis. Cluster (≥10 diverticula) type (OR, 4.0; 95% CI, 1.8–8.9), hypertension (OR, 2.2; 95% CI, 1.0–4.6), ischemic heart disease (OR, 2.4; 95% CI, 1.1–5.4), and chronic renal failure (OR, 6.4; 95% CI, 1.3–32) were independent risk factors for diverticular bleeding. CONCLUSIONS: Large number of diverticula, hypertension, and concomitant arteriosclerotic diseases including ischemic heart disease and chronic renal failure are risk factors for diverticular bleeding. This study identifies new information on the risk factors for diverticular bleeding. Springer-Verlag 2012-02-22 2012 /pmc/articles/PMC3430839/ /pubmed/22354135 http://dx.doi.org/10.1007/s00384-012-1422-x Text en © The Author(s) 2012 https://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Niikura, Ryota Nagata, Naoyoshi Akiyama, Junichi Shimbo, Takuro Uemura, Naomi Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title | Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title_full | Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title_fullStr | Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title_full_unstemmed | Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title_short | Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
title_sort | hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case–control study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430839/ https://www.ncbi.nlm.nih.gov/pubmed/22354135 http://dx.doi.org/10.1007/s00384-012-1422-x |
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