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Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp

Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department fo...

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Autores principales: Charfi, Slim, Kallel, Rim, Mnif, Hela, Ellouze, Sameh, Dhouib, Mohamed, Guermazi, Mohamed, Khabir, Abdelmajid, Sellami-Boudawara, Tahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431066/
https://www.ncbi.nlm.nih.gov/pubmed/22953093
http://dx.doi.org/10.1155/2012/358302
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author Charfi, Slim
Kallel, Rim
Mnif, Hela
Ellouze, Sameh
Dhouib, Mohamed
Guermazi, Mohamed
Khabir, Abdelmajid
Sellami-Boudawara, Tahya
author_facet Charfi, Slim
Kallel, Rim
Mnif, Hela
Ellouze, Sameh
Dhouib, Mohamed
Guermazi, Mohamed
Khabir, Abdelmajid
Sellami-Boudawara, Tahya
author_sort Charfi, Slim
collection PubMed
description Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear.
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spelling pubmed-34310662012-09-05 Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp Charfi, Slim Kallel, Rim Mnif, Hela Ellouze, Sameh Dhouib, Mohamed Guermazi, Mohamed Khabir, Abdelmajid Sellami-Boudawara, Tahya Case Rep Obstet Gynecol Case Report Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear. Hindawi Publishing Corporation 2012 2012-08-16 /pmc/articles/PMC3431066/ /pubmed/22953093 http://dx.doi.org/10.1155/2012/358302 Text en Copyright © 2012 Slim Charfi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Charfi, Slim
Kallel, Rim
Mnif, Hela
Ellouze, Sameh
Dhouib, Mohamed
Guermazi, Mohamed
Khabir, Abdelmajid
Sellami-Boudawara, Tahya
Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title_full Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title_fullStr Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title_full_unstemmed Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title_short Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
title_sort mullerian adenosaroma of the cervix with sarcomatous overgrowth and heterologous elements presenting as a recurrent cervical polyp
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431066/
https://www.ncbi.nlm.nih.gov/pubmed/22953093
http://dx.doi.org/10.1155/2012/358302
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