Cargando…
Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp
Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department fo...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431066/ https://www.ncbi.nlm.nih.gov/pubmed/22953093 http://dx.doi.org/10.1155/2012/358302 |
_version_ | 1782242022406488064 |
---|---|
author | Charfi, Slim Kallel, Rim Mnif, Hela Ellouze, Sameh Dhouib, Mohamed Guermazi, Mohamed Khabir, Abdelmajid Sellami-Boudawara, Tahya |
author_facet | Charfi, Slim Kallel, Rim Mnif, Hela Ellouze, Sameh Dhouib, Mohamed Guermazi, Mohamed Khabir, Abdelmajid Sellami-Boudawara, Tahya |
author_sort | Charfi, Slim |
collection | PubMed |
description | Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear. |
format | Online Article Text |
id | pubmed-3431066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34310662012-09-05 Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp Charfi, Slim Kallel, Rim Mnif, Hela Ellouze, Sameh Dhouib, Mohamed Guermazi, Mohamed Khabir, Abdelmajid Sellami-Boudawara, Tahya Case Rep Obstet Gynecol Case Report Mullerian adenosarcoma of the cervix is a rare tumor composed of benign epithelial and malignant stromal components. Sarcomatous overgrowth and heterologous elements in cervical adenosarcoma are extremely infrequent. We report the case of a 26-year-old woman admitted at the gynaecology department for a painless mass protruding from her vagina. The initial pathological exam concluded to endocervical polyp. Six months later, the patient was readmitted with a recurrence of the polyp. The pathological exam demonstrated interlacing fascicles of elongated spindle cells with few mitotic activity and no glandular formation. After reviewing of the initial polyp the diagnosis of mullerian adenosarcoma was suggested. A second recurrence of the polyp was noted one month later. Histopathological exam of the recurrent polyp confirmed the diagnosis of adenosarcoma with sarcomatous overgrowth and heterologous elements. The patient was lost for follow-up. Cervical adenosarcoma with sarcomatous overgrowth and heterologous element is a rare tumor that occurs in younger age in contrast to endometrium/corpus uterin mullerian adenosarcoma. In young women with recurrent cervical polyp, mullerian adenosarcoma must be considered and should be excluded by careful histopathological exam. Sarcomatous overgrowth and myometrial invasion are the most important prognostic factors. Treatment strategy is still unclear. Hindawi Publishing Corporation 2012 2012-08-16 /pmc/articles/PMC3431066/ /pubmed/22953093 http://dx.doi.org/10.1155/2012/358302 Text en Copyright © 2012 Slim Charfi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Charfi, Slim Kallel, Rim Mnif, Hela Ellouze, Sameh Dhouib, Mohamed Guermazi, Mohamed Khabir, Abdelmajid Sellami-Boudawara, Tahya Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_full | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_fullStr | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_full_unstemmed | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_short | Mullerian Adenosaroma of the Cervix with Sarcomatous Overgrowth and Heterologous Elements Presenting as a Recurrent Cervical Polyp |
title_sort | mullerian adenosaroma of the cervix with sarcomatous overgrowth and heterologous elements presenting as a recurrent cervical polyp |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431066/ https://www.ncbi.nlm.nih.gov/pubmed/22953093 http://dx.doi.org/10.1155/2012/358302 |
work_keys_str_mv | AT charfislim mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT kallelrim mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT mnifhela mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT ellouzesameh mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT dhouibmohamed mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT guermazimohamed mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT khabirabdelmajid mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp AT sellamiboudawaratahya mullerianadenosaromaofthecervixwithsarcomatousovergrowthandheterologouselementspresentingasarecurrentcervicalpolyp |