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Vitiligo in a Patient Treated with Interferon Alpha-2a for Behçet's Disease

Behçet's disease (BD) and vitiligo are diseases of unknown etiology. Interferon (IFN) alpha therapy is commonly used in Behçet uveitis. Interferon treatment in various diseases have also been observed causing certain autoimmune diseases such as vitiligo because of its immunomodulatory activity....

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Detalles Bibliográficos
Autores principales: Guney, Esra, Akcali, Gulunay, Akcay, Betul Ilkay, Unlu, Cihan, Erdogan, Gurkan, Bozkurt, Tahir Kansu, Bayramlar, Huseyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431079/
https://www.ncbi.nlm.nih.gov/pubmed/22952476
http://dx.doi.org/10.1155/2012/387140
Descripción
Sumario:Behçet's disease (BD) and vitiligo are diseases of unknown etiology. Interferon (IFN) alpha therapy is commonly used in Behçet uveitis. Interferon treatment in various diseases have also been observed causing certain autoimmune diseases such as vitiligo because of its immunomodulatory activity. The association between IFN therapy and vitiligo has been reported in the literature. We report a 21-year-old man with BD in whom vitiligo occurred during IFN treatment. To the best of our knowledge, this is the first reported case of such an association.