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Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone
Btg1 belongs to a family of cell cycle inhibitory genes. We observed that Btg1 is highly expressed in adult neurogenic niches, i.e., the dentate gyrus and subventricular zone (SVZ). Thus, we generated Btg1 knockout mice to analyze the role of Btg1 in the process of generation of adult new neurons. A...
Autores principales: | Farioli-Vecchioli, Stefano, Micheli, Laura, Saraulli, Daniele, Ceccarelli, Manuela, Cannas, Sara, Scardigli, Raffaella, Leonardi, Luca, Cinà, Irene, Costanzi, Marco, Ciotti, Maria Teresa, Moreira, Pedro, Rouault, Jean-Pierre, Cestari, Vincenzo, Tirone, Felice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431174/ https://www.ncbi.nlm.nih.gov/pubmed/22969701 http://dx.doi.org/10.3389/fnins.2012.00124 |
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