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Yes-Associated Protein Regulates the Hepatic Response After Bile Duct Ligation
Human chronic cholestatic liver diseases are characterized by cholangiocyte proliferation, hepatocyte injury, and fibrosis. Yes-associated protein (YAP), the effector of the Hippo tumor-suppressor pathway, has been shown to play a critical role in promoting cholangiocyte and hepatocyte proliferation...
Autores principales: | Bai, Haibo, Zhang, Nailing, Xu, Yang, Chen, Qian, Khan, Mehtab, Potter, James J, Nayar, Suresh K, Cornish, Toby, Alpini, Gianfranco, Bronk, Steven, Pan, Duojia, Anders, Robert A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431197/ https://www.ncbi.nlm.nih.gov/pubmed/22886419 http://dx.doi.org/10.1002/hep.25769 |
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