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Shrinking the Metabolic Solution Space Using Experimental Datasets
Constraint-based models of metabolism have been used in a variety of studies on drug discovery, metabolic engineering, evolution, and multi-species interactions. These genome-scale models can be generated for any sequenced organism since their main parameters (i.e., reaction stoichiometry) are highl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431291/ https://www.ncbi.nlm.nih.gov/pubmed/22956899 http://dx.doi.org/10.1371/journal.pcbi.1002662 |