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Drosophila melanogaster Acetyl-CoA-Carboxylase Sustains a Fatty Acid–Dependent Remote Signal to Waterproof the Respiratory System

Fatty acid (FA) metabolism plays a central role in body homeostasis and related diseases. Thus, FA metabolic enzymes are attractive targets for drug therapy. Mouse studies on Acetyl-coenzymeA-carboxylase (ACC), the rate-limiting enzyme for FA synthesis, have highlighted its homeostatic role in liver...

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Detalles Bibliográficos
Autores principales: Parvy, Jean-Philippe, Napal, Laura, Rubin, Thomas, Poidevin, Mickael, Perrin, Laurent, Wicker-Thomas, Claude, Montagne, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431307/
https://www.ncbi.nlm.nih.gov/pubmed/22956916
http://dx.doi.org/10.1371/journal.pgen.1002925