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Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program
Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a...
Autores principales: | Pollin, Toni I., Isakova, Tamara, Jablonski, Kathleen A., de Bakker, Paul I. W., Taylor, Andrew, McAteer, Jarred, Pan, Qing, Horton, Edward S., Delahanty, Linda M., Altshuler, David, Shuldiner, Alan R., Goldberg, Ronald B., Florez, Jose C., Franks, Paul W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431328/ https://www.ncbi.nlm.nih.gov/pubmed/22951888 http://dx.doi.org/10.1371/journal.pgen.1002895 |
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