p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

While p73 overexpression has been associated with increased apoptosis in cancer tissues, p73 overexpressing tumors appear to be of high grade malignancy. Why this putative tumor suppressor is overexpressed in cancer cells and what the function of overexpressed p73 is in breast cancers are critical q...

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Detalles Bibliográficos
Autores principales: Tophkhane, Chaitali, Yang, Shi-He, Jiang, Yunbo, Ma, Zhikun, Subramaniam, Dharmalingam, Anant, Shrikant, Yogosawa, Shingo, Sakai, Toshiyuki, Liu, Wan-Guo, Edgerton, Susan, Thor, Ann, Yang, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431388/
https://www.ncbi.nlm.nih.gov/pubmed/22952705
http://dx.doi.org/10.1371/journal.pone.0043564

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