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Toxicokinetic-toxicodynamic modelling of survival of Gammarus pulex in multiple pulse exposures to propiconazole: model assumptions, calibration data requirements and predictive power

Toxicokinetic-toxicodynamic (TKTD) models quantify the time-course of internal concentration, which is defined by uptake, elimination and biotransformation (TK), and the processes which lead to the toxic effects (TD). TKTD models show potential in predicting pesticide effects in fluctuating concentr...

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Detalles Bibliográficos
Autores principales:	Nyman, Anna-Maija, Schirmer, Kristin, Ashauer, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431474/ https://www.ncbi.nlm.nih.gov/pubmed/22562719 http://dx.doi.org/10.1007/s10646-012-0917-0

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