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Structural determinants of Ca(V)1.3 L-type calcium channel gating

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A C-terminal modulatory domain (CTM) tightly regulates the biophysical properties of Ca(v)1.3 L-type Ca(2+) channels, in particular the voltage dependence of activation (V(0.5)) and Ca(2+) dependent inactivation (CDI). A functional CTM is present in the long C-terminus of human and mouse Ca(v)1.3 (C...

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Detalles Bibliográficos
Autores principales:	Lieb, Andreas, Scharinger, Anja, Sartori, Simone, Sinnegger-Brauns, Martina J., Striessnig, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431584/ https://www.ncbi.nlm.nih.gov/pubmed/22760075 http://dx.doi.org/10.4161/chan.21002

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