Cargando…
Matrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels
Photoreceptor cyclic nucleotide-gated (CNG) channels are the principal ion channels responsible for transduction of the light-induced change in cGMP concentration into an electrical signal. The ligand sensitivity of photoreceptor CNG channels is subject to regulation by intracellular signaling effec...
Autores principales: | Meighan, Peter C., Meighan, Starla E., Rich, Elizabeth D., Brown, R. Lane, Varnum, Michael D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431585/ https://www.ncbi.nlm.nih.gov/pubmed/22699690 http://dx.doi.org/10.4161/chan.20904 |
Ejemplares similares
-
Inherited macular degeneration-associated mutations in CNGB3 increase the ligand sensitivity and spontaneous open probability of cone cyclic nucleotide-gated channels
por: Meighan, Peter C., et al.
Publicado: (2015) -
Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel
por: Hu, Zhengshan, et al.
Publicado: (2023) -
Cyclic Nucleotide-gated Ion Channels in Rod Photoreceptors Are Protected from Retinoid Inhibition
por: He, Quanhua, et al.
Publicado: (2006) -
C-Linker of Cyclic Nucleotide–gated Channels Controls Coupling of Ligand Binding to Channel Gating
por: Paoletti, Pierre, et al.
Publicado: (1999) -
Calcium Modulation of Ligand Affinity in the Cyclic GMP–gated Ion Channels of Cone Photoreceptors
por: Hackos, David H., et al.
Publicado: (1997)