GQ-16, a Novel Peroxisome Proliferator-activated Receptor γ (PPARγ) Ligand, Promotes Insulin Sensitization without Weight Gain

The recent discovery that peroxisome proliferator-activated receptor γ (PPARγ) targeted anti-diabetic drugs function by inhibiting Cdk5-mediated phosphorylation of the receptor has provided a new viewpoint to evaluate and perhaps develop improved insulin-sensitizing agents. Herein we report the deve...

Descripción completa

Detalles Bibliográficos
Autores principales: Amato, Angélica A., Rajagopalan, Senapathy, Lin, Jean Z., Carvalho, Bruno M., Figueira, Ana C. M., Lu, Jenny, Ayers, Stephen D., Mottin, Melina, Silveira, Rodrigo L., Souza, Paulo C. T., Mourão, Rosa H. V., Saad, Mário J. A., Togashi, Marie, Simeoni, Luiz A., Abdalla, Dulcinéia S. P., Skaf, Munir S., Polikparpov, Igor, Lima, Maria C. A., Galdino, Suely L., Brennan, Richard G., Baxter, John D., Pitta, Ivan R., Webb, Paul, Phillips, Kevin J., Neves, Francisco A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431672/
https://www.ncbi.nlm.nih.gov/pubmed/22584573
http://dx.doi.org/10.1074/jbc.M111.332106

Ejemplares similares

Ejemplares similares