Cargando…

Combined Phosphatase and Tensin Homolog (PTEN) Loss and Fatty Acid Synthase (FAS) Overexpression Worsens the Prognosis of Chinese Patients with Hepatocellular Carcinoma

We aimed to investigate the expression pattern of phosphatase and tensin homolog (PTEN), to evaluate the relationship between PTEN expression and clinicopathological characteristics, including fatty acid synthase (FAS) expression, and to determine the correlations of PTEN and FAS expression with sur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Xuehua, Qin, Xia, Fei, Maogui, Hou, Wenmin, Greshock, Joel, Bachman, Kurtis E., Wooster, Richard, Kang, Jiuhong, Qin, Crystal Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431841/ https://www.ncbi.nlm.nih.gov/pubmed/22949843 http://dx.doi.org/10.3390/ijms13089980

Ejemplares similares

Loss and reduced expression of PTEN correlate with advanced-stage gastric carcinoma
por: ZHU, XUEHUA, et al.
Publicado: (2013)

High overexpression of fatty acid synthase is associated with poor survival in Chinese patients with gastric carcinoma
por: HOU, WENMIN, et al.
Publicado: (2012)

Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors
por: Xu, Wenting, et al.
Publicado: (2014)

New Treatment Opportunities in Phosphatase and Tensin Homolog (PTEN)-Deficient Tumors: Focus on PTEN/Focal Adhesion Kinase Pathway
por: Alfieri, Roberta, et al.
Publicado: (2017)

A comprehensive analysis of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) loss in colorectal cancer
por: Lin, Pei-Ching, et al.
Publicado: (2015)

Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis
por: Blüml, Stephan, et al.
Publicado: (2015)

Phosphatase and tensin homolog (PTEN) is down-regulated in human NK/T-cell lymphoma and corrects with clinical outcomes
por: Fu, Xiaorui, et al.
Publicado: (2017)

Loss of phosphatase activity in PTEN (phosphatase and tensin homolog deleted on chromosome ten) results in endometrial carcinoma in humans: An in-silico study
por: Mondal, Sunil Kanti, et al.
Publicado: (2020)

Different Conformations of Phosphatase and Tensin Homolog, Deleted on Chromosome 10 (PTEN) Protein within the Nucleus and Cytoplasm of Neurons
por: Moncalero, Vera L., et al.
Publicado: (2011)

Effect of Aging and Dietary Salt and Potassium Intake on Endothelial PTEN (Phosphatase and Tensin Homolog on Chromosome 10) Function
por: Ying, Wei-Zhong, et al.
Publicado: (2012)

Phosphatase and Tensin Homolog (PTEN) Expression as a Surrogate Biomarker Correlated With the Depth of Invasion in Cutaneous Malignant Melanoma
por: Sun, Ziyi, et al.
Publicado: (2023)

Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity
por: Wong, J. T., et al.
Publicado: (2006)

High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer
por: Liu, Shufang, et al.
Publicado: (2018)

Phosphatase and tensin homolog (PTEN) expression on oncologic outcome in renal cell carcinoma: A systematic review and meta-analysis
por: Tang, Lu, et al.
Publicado: (2017)

Phosphatase and Tensin Homolog (PTEN) of Japanese Flounder—Its Regulation by miRNA and Role in Autophagy, Apoptosis and Pathogen Infection
por: Li, Wenrui, et al.
Publicado: (2020)

The Prognostic Significance of Phosphatase and Tensin Homolog Loss in Breast Cancer
por: Windarti, Indri, et al.
Publicado: (2019)

Sex differences in skeletal muscle Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) levels: A cross-sectional study
por: Samaan, M. Constantine, et al.
Publicado: (2015)

Interactions of Phosphatase and Tensin Homologue (PTEN) Proteins with Phosphatidylinositol Phosphates: Insights from Molecular Dynamics Simulations of PTEN and Voltage Sensitive Phosphatase
por: Kalli, Antreas C., et al.
Publicado: (2014)

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy
por: Abbotts, Rachel, et al.
Publicado: (2014)

Suppression of miR-21 Expression Inhibits Cell Proliferation and Migration of Liver Cancer Cells by Targeting Phosphatase and Tensin Homolog (PTEN)
por: Liu, Haiwei, et al.
Publicado: (2018)

Neuroprotective and Anti-Inflammatory Roles of the Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy
por: Grande, Valentina, et al.
Publicado: (2014)

miR-486 Promotes Capan-2 Pancreatic Cancer Cell Proliferation by Targeting Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)
por: Xia, Lu, et al.
Publicado: (2019)

Silymarin Induces Insulin Resistance through an Increase of Phosphatase and Tensin Homolog in Wistar Rats
por: Cheng, Kai-Chun, et al.
Publicado: (2014)

Immunohistochemical expression of phosphatase and tensin homolog in histologic gradings of oral squamous cell carcinoma
por: Jasphin, Shiny S. R., et al.
Publicado: (2016)

SHCBP1 regulates apoptosis in lung cancer cells through phosphatase and tensin homolog
por: Wang, Fei, et al.
Publicado: (2019)

Study of the Association of Phosphatase and Tensin Homolog and p27 Expressions in Endometrial Hyperplasia and Carcinoma
por: Atta, Ihab Shafek
Publicado: (2019)

Phosphatase and tensin homolog overexpression decreases proliferation and invasion and increases apoptosis in oral squamous cell carcinoma cells
por: GAO, QI, et al.
Publicado: (2014)

Micro-RNA 205-5p is Involved in the Progression of Gastric Cancer and Targets Phosphatase and Tensin Homolog (PTEN) in SGC-7901 Human Gastric Cancer Cells
por: Yao, Lina, et al.
Publicado: (2019)

Genetic networks in the mouse retina: Growth Associated Protein 43 and Phosphatase Tensin Homolog network
por: Freeman, Natalie E., et al.
Publicado: (2011)

Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy
por: Tang, Ying, et al.
Publicado: (2015)

Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain
por: Huang, Shi-Ying, et al.
Publicado: (2015)

Phosphatase and Tensin Homolog in Non-neoplastic Digestive Disease: More Than Just Tumor Suppressor
por: He, Tianyu, et al.
Publicado: (2021)

Phosphatase and Tensin Homolog Mutation in Immune Cell Infiltration and Clinicopathological Features of Low-Grade Gliomas
por: Feng, Peng, et al.
Publicado: (2020)

Proteus-Like Syndrome: A Rare Phenotype of Phosphatase and Tensin Homolog Hamartoma Tumor Syndrome
por: Abu-Shaban, Kamil, et al.
Publicado: (2022)

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) and PH Domain and Leucine-rich Repeat Phosphatase Cross-talk (PHLPP) in Cancer Cells and in Transforming Growth Factor β-Activated Stem Cells
por: Ghalali, Aram, et al.
Publicado: (2014)

Doxycycline Attenuates Atrial Remodeling by Interfering with MicroRNA-21 and Downstream Phosphatase and Tensin Homolog (PTEN)/Phosphoinositide 3-Kinase (PI3K) Signaling Pathway
por: Zhang, Kai, et al.
Publicado: (2018)

Knockdown of Phospholipase Cɛ (PLCɛ) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer
por: Wang, Xiao, et al.
Publicado: (2018)

Phosphatase and tensin homologue deleted on chromosome 10
por: Abdulkareem, Imran Haruna, et al.
Publicado: (2013)

Differential Expression and Clinical Significance of DNA Methyltransferase 3B (DNMT3B), Phosphatase and Tensin Homolog (PTEN) and Human MutL Homologs 1 (hMLH1) in Endometrial Carcinomas
por: Li, Wenting, et al.
Publicado: (2017)

TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma
por: Tellios, Nikoleta, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7ji2n5pt4dce7mhv9i09irkd8c