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Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2

We provide a theory for employing Förster resonance energy transfer (FRET) measurements to determine altered heteropentameric ion channel stoichiometries in intracellular compartments of living cells. We simulate FRET within nicotinic receptors (nAChRs) whose α4 and β2 subunits contain acceptor and...

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Detalles Bibliográficos
Autores principales: Srinivasan, Rahul, Richards, Christopher I., Dilworth, Crystal, Moss, Fraser J., Dougherty, Dennis A., Lester, Henry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431844/
https://www.ncbi.nlm.nih.gov/pubmed/22949846
http://dx.doi.org/10.3390/ijms130810022