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Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2
We provide a theory for employing Förster resonance energy transfer (FRET) measurements to determine altered heteropentameric ion channel stoichiometries in intracellular compartments of living cells. We simulate FRET within nicotinic receptors (nAChRs) whose α4 and β2 subunits contain acceptor and...
Autores principales: | Srinivasan, Rahul, Richards, Christopher I., Dilworth, Crystal, Moss, Fraser J., Dougherty, Dennis A., Lester, Henry A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431844/ https://www.ncbi.nlm.nih.gov/pubmed/22949846 http://dx.doi.org/10.3390/ijms130810022 |
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