An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity

A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is th...

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Detalles Bibliográficos
Autores principales: Liao, Yu-Ren, Kuo, Ping-Chung, Liang, Jun-Weil, Shen, Yuh-Chiang, Wu, Tian-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431870/
https://www.ncbi.nlm.nih.gov/pubmed/22949872
http://dx.doi.org/10.3390/ijms130810432
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author Liao, Yu-Ren
Kuo, Ping-Chung
Liang, Jun-Weil
Shen, Yuh-Chiang
Wu, Tian-Shung
author_facet Liao, Yu-Ren
Kuo, Ping-Chung
Liang, Jun-Weil
Shen, Yuh-Chiang
Wu, Tian-Shung
author_sort Liao, Yu-Ren
collection PubMed
description A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo.
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spelling pubmed-34318702012-09-04 An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity Liao, Yu-Ren Kuo, Ping-Chung Liang, Jun-Weil Shen, Yuh-Chiang Wu, Tian-Shung Int J Mol Sci Article A naturally occurring enynyl-benzenoid, benzocamphorin F (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo. Molecular Diversity Preservation International (MDPI) 2012-08-21 /pmc/articles/PMC3431870/ /pubmed/22949872 http://dx.doi.org/10.3390/ijms130810432 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Liao, Yu-Ren
Kuo, Ping-Chung
Liang, Jun-Weil
Shen, Yuh-Chiang
Wu, Tian-Shung
An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title_full An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title_fullStr An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title_full_unstemmed An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title_short An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent, Benzocamphorin F, and Its Anti-Inflammatory Activity
title_sort efficient total synthesis of a potent anti-inflammatory agent, benzocamphorin f, and its anti-inflammatory activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431870/
https://www.ncbi.nlm.nih.gov/pubmed/22949872
http://dx.doi.org/10.3390/ijms130810432
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