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Nanotheranostics – a review of recent publications
Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431969/ https://www.ncbi.nlm.nih.gov/pubmed/22956869 http://dx.doi.org/10.2147/IJN.S33065 |
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author | Wang, Li-Sheng Chuang, Min-Chieh Ho, Ja-an Annie |
author_facet | Wang, Li-Sheng Chuang, Min-Chieh Ho, Ja-an Annie |
author_sort | Wang, Li-Sheng |
collection | PubMed |
description | Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented. |
format | Online Article Text |
id | pubmed-3431969 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-34319692012-09-06 Nanotheranostics – a review of recent publications Wang, Li-Sheng Chuang, Min-Chieh Ho, Ja-an Annie Int J Nanomedicine Review Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented. Dove Medical Press 2012 2012-08-23 /pmc/articles/PMC3431969/ /pubmed/22956869 http://dx.doi.org/10.2147/IJN.S33065 Text en © 2012 Wang et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Wang, Li-Sheng Chuang, Min-Chieh Ho, Ja-an Annie Nanotheranostics – a review of recent publications |
title | Nanotheranostics – a review of recent publications |
title_full | Nanotheranostics – a review of recent publications |
title_fullStr | Nanotheranostics – a review of recent publications |
title_full_unstemmed | Nanotheranostics – a review of recent publications |
title_short | Nanotheranostics – a review of recent publications |
title_sort | nanotheranostics – a review of recent publications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431969/ https://www.ncbi.nlm.nih.gov/pubmed/22956869 http://dx.doi.org/10.2147/IJN.S33065 |
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