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Nanotheranostics – a review of recent publications

Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostic...

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Detalles Bibliográficos
Autores principales: Wang, Li-Sheng, Chuang, Min-Chieh, Ho, Ja-an Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431969/
https://www.ncbi.nlm.nih.gov/pubmed/22956869
http://dx.doi.org/10.2147/IJN.S33065
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author Wang, Li-Sheng
Chuang, Min-Chieh
Ho, Ja-an Annie
author_facet Wang, Li-Sheng
Chuang, Min-Chieh
Ho, Ja-an Annie
author_sort Wang, Li-Sheng
collection PubMed
description Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented.
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spelling pubmed-34319692012-09-06 Nanotheranostics – a review of recent publications Wang, Li-Sheng Chuang, Min-Chieh Ho, Ja-an Annie Int J Nanomedicine Review Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented. Dove Medical Press 2012 2012-08-23 /pmc/articles/PMC3431969/ /pubmed/22956869 http://dx.doi.org/10.2147/IJN.S33065 Text en © 2012 Wang et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Wang, Li-Sheng
Chuang, Min-Chieh
Ho, Ja-an Annie
Nanotheranostics – a review of recent publications
title Nanotheranostics – a review of recent publications
title_full Nanotheranostics – a review of recent publications
title_fullStr Nanotheranostics – a review of recent publications
title_full_unstemmed Nanotheranostics – a review of recent publications
title_short Nanotheranostics – a review of recent publications
title_sort nanotheranostics – a review of recent publications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431969/
https://www.ncbi.nlm.nih.gov/pubmed/22956869
http://dx.doi.org/10.2147/IJN.S33065
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