Biochemical and Mass Spectrometric Characterization of Human N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition

The mechanism of inactivation of human enzyme N-acylethanolamine-hydrolyzing acid amidase (hNAAA), with selected inhibitors identified in a novel fluorescent based assay developed for characterization of both reversible and irreversible inhibitors, was investigated kinetically and using matrix-assis...

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Detalles Bibliográficos
Autores principales: West, Jay M., Zvonok, Nikolai, Whitten, Kyle M., Vadivel, Subramanian K., Bowman, Anna L., Makriyannis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432061/
https://www.ncbi.nlm.nih.gov/pubmed/22952796
http://dx.doi.org/10.1371/journal.pone.0043877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432061/
https://www.ncbi.nlm.nih.gov/pubmed/22952796
http://dx.doi.org/10.1371/journal.pone.0043877

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